產品詳情
簡單介紹：
Anti-Phospho-PDPK1(Tyr373 + Tyr376)抗體產品質量穩定，實驗效果明顯，貨期快，價格優惠，歡迎垂詢訂購！我公司長期供應**組化抗體、WB抗體、**組化試劑盒和抗體試驗所需全部相關試劑、熒光標記抗體、單克隆抗體、多克隆抗體、各種標記的二抗IgG/IgM/IgD/IgA等科研實驗抗體。Anti-Phospho-PDPK1(Tyr373 + Tyr376)抗體用于**組化實驗,WB實驗,相應的標記抗體有HRP標記抗體,FITC標記,BIO等。
詳情介紹：
Rabbit Anti-Phospho-PDPK1(Tyr373 + Tyr376)
Cat. Number:
Anti-Phospho-PDPK1(Tyr373 + Tyr376)抗體KL-3017R
Quantity size:
0.1ml
Concentration:
1mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
PDK1 (3 Phosphoinositide Dependent Protein Kinase 1) phosphorylates AGC kinases. PDK1 activates conventional PKC and Anti-Phospho-PDPK1(Tyr373 + Tyr376)抗體PKC zeta through phosphorylation of critical threonine residues in the activation loop. PDK1 also phosphorylates Protein Kinase B (PKB) at threonine 308 in the presence of phosphatidylinositol-3,4,5-trisphosphate. Active Akt inactivates Glycogen Synthase Kinase 3 (GSK3), eventually leading to the dephosphorylation and activation of glycogen synthase and the stimulation of glycogen synthesis. Because of the role that PDK plays in insulin-induced glycogen synthesis and PKC activation it is a potentially important target for metabolic drug research. There are three named isoforms.
Also known as:
PDPK1(Phospho Tyr373 + Tyr376);Anti-Phospho-PDPK1(Tyr373 + Tyr376)抗體 PDPK1(Phospho Y373 + Y376); 3 phosphoinositide dependent protein kinase 1; hPDK 1; hPDK1; MGC20087 MGC35290; PDK 1; PDPK 1; PDPK1; PkB kinase; PkB kinase like gene 1; PkB like 1; PkB like; PRO0461.
Specificity:
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Rabbit Polyclonal IgG, affinity purified by Protein A.
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Reacts with: Human, Mouse, Rat, Anti-Phospho-PDPK1(Tyr373 + Tyr376)抗體Chicken, Dog, Pig, Cow, .
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Immunogen: KLH conjugated Synthesised phosphopeptide derived from human PDPK1 around the phosphorylation site of (Y373+Y376).
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Predicted Molecular Weight: 61kDa.
Storage:
Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
Not yet tested in other applications. Anti-Phospho-PDPK1(Tyr373 + Tyr376)抗體
Optimal working dilutions must be determined by the end user.
Not yet tested in other applications. Anti-Phospho-PDPK1(Tyr373 + Tyr376)抗體
Optimal working dilutions must be determined by the end user.
