產品詳情
簡單介紹：
Anti-MSC/Musculin抗體產品質量穩定，實驗效果明顯，貨期快，價格優惠，歡迎垂詢訂購！我公司長期供應**組化抗體、WB抗體、**組化試劑盒和抗體試驗所需全部相關試劑、熒光標記抗體、單克隆抗體、多克隆抗體、各種標記的二抗IgG/IgM/IgD/IgA等科研實驗抗體。Anti-MSC/Musculin抗體用于**組化實驗,WB實驗,相應的標記抗體有HRP標記抗體,FITC標記,BIO等。
詳情介紹：
Rabbit Anti-MSC/Musculin
Cat. Number:
Anti-MSC/Musculin抗體KL-17847R
Quantity size:
0.2ml
Concentration:
1mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
Differentiation of myogenic cells is regulated by multiple positively and negatively acting factors. One well characterized family of helix-loop-helix (HLH) proteins, known to play an important role in the regulation of muscle cell development, includes Myo D, myogenin and musculin (also designated MyoR). Members of this group of transcription factors form heterodimers with products of a more widely expressed family of bHLH genes, the E family, which consists of at least three distinct genes: E2A, IF2 and HEB. Myo D-E or Anti-MSC/Musculin抗體musculin-E heterodimers bind avidly to consensus E box motifs, which are functionally important elements in the promoter regions of many muscle-specific terminal differentiation genes. Myo D complexes potently induce transcriptional activation, while musculin complexes bind adjacent to Myo D DNA-binding regions to represses Myo D activity, which then results in the delayed expression of muscle-specific genes. Musculin is highly expressed in undifferentiated and proliferating myoblasts in culture, and its expression is down regulated during myogenesis and at the onset of terminal differentiation.
Also known as:
ABF-1; ABF1; Activated B cell factor 1; Anti-MSC/Musculin抗體Activated B-cell factor 1; bHLHa22; Class A basic helix-loop-helix protein 22; Msc; MUSC_HUMAN; Musculin; MYOR.
Specificity:
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Rabbit Polyclonal IgG, affinity purified by Protein A.
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Reacts with: Human, Mouse, Rat, Chicken, Dog, Cow, Horse, Guinea Pig, .
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Immunogen: KLH conjugated syntheticAnti-MSC/Musculin抗體 peptide derived from mouse MSC/Musculin.
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Predicted Molecular Weight: 21kDa.
Storage:
Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 Anti-MSC/Musculin抗體
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.
