產(chǎn)品詳情
簡(jiǎn)單介紹：
Anti-phospho-LIM Kinase 1 (Thr508)抗體產(chǎn)品質(zhì)量穩(wěn)定，實(shí)驗(yàn)效果明顯，貨期快，價(jià)格優(yōu)惠，歡迎垂詢訂購(gòu)！我公司長(zhǎng)期供應(yīng)**組化抗體、WB抗體、**組化試劑盒和抗體試驗(yàn)所需全部相關(guān)試劑、熒光標(biāo)記抗體、單克隆抗體、多克隆抗體、各種標(biāo)記的二抗IgG/IgM/IgD/IgA等科研實(shí)驗(yàn)抗體。Anti-phospho-LIM Kinase 1 (Thr508)抗體用于**組化實(shí)驗(yàn),WB實(shí)驗(yàn),相應(yīng)的標(biāo)記抗體有HRP標(biāo)記抗體,FITC標(biāo)記,BIO等。
詳情介紹：
Rabbit Anti-phospho-LIM Kinase 1 (Thr508)
Cat. Number:
Anti-phospho-LIM Kinase 1 (Thr508)抗體KL-18256R
Quantity size:
0.1ml
Concentration:
1mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
There are approximately 40 known eukaryotic LIM proteins, so named for the LIM domains they contain. LIM domains are highly conserved cysteine-rich structures containing 2 zinc fingers. Although zinc fingers usually function by binding to DNA or RNA, the LIM motif probably mediates protein-protein interactions. LIM kinase-1 and LIM kinase-2 belong to a small subfamily with a unique combination of 2 N-terminal LIM Anti-phospho-LIM Kinase 1 (Thr508)抗體motifs and a C-terminal protein kinase domain. LIMK1 is a serine/threonine kinase that regulates actin polymerization via phosphorylation and inactivation of the actin binding factor cofilin. This protein is ubiquitously expressed during development and plays a role in many cellular processes associated with cytoskeletal structure. This protein also stimulates axon growth and may play a role in brain development. LIMK1 hemizygosity is implicated in the impaired visuospatial constructive cognition of Williams syndrome. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Feb 2011]
Also known as:
LIM Kinase 1 (phospho T508); p-LIM Kinase 1 Anti-phospho-LIM Kinase 1 (Thr508)抗體(phospho T508); LIMK1 (phospho T508);p-LIMK1 (phospho T508); EC 2.7.1.37; LIM domain containing protein kinase; LIM domain kinase 1; LIM motif containing protein kinase; LIMK 1; LIMK; LIMK-1; limk1; LIMK1_HUMAN.
Specificity:
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Rabbit Polyclonal IgG, affinity purified by Protein A.
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Reacts with: Human, Mouse, Rat, Chicken, Pig, Cow, Horse, Sheep, .
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Immunogen: KLH conjugated synthesised Anti-phospho-LIM Kinase 1 (Thr508)抗體phosphopeptide derived from human LIM Kinase 1 around the phosphorylation site of Thr508.
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Predicted Molecular Weight: 73kDa.
Storage:
Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
Not yet tested in other applications. Anti-phospho-LIM Kinase 1 (Thr508)抗體
Optimal working dilutions must be determined by the end user.
Not yet tested in other applications. Anti-phospho-LIM Kinase 1 (Thr508)抗體
Optimal working dilutions must be determined by the end user.
