產品詳情
簡單介紹：
Anti-Diphtheria toxin fragment A抗體產品質量穩定，實驗效果明顯，貨期快，價格優惠，歡迎垂詢訂購！我公司長期供應**組化抗體、WB抗體、**組化試劑盒和抗體試驗所需全部相關試劑、熒光標記抗體、單克隆抗體、多克隆抗體、各種標記的二抗IgG/IgM/IgD/IgA等科研實驗抗體。Anti-Diphtheria toxin fragment A抗體用于**組化實驗,WB實驗,相應的標記抗體有HRP標記抗體,FITC標記,BIO等。
詳情介紹：
Rabbit Anti-Diphtheria toxin fragment A
Cat. Number:
Anti-Diphtheria toxin fragment A抗體KL-10667R
Quantity size:
0.2ml
Concentration:
1mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
Diphtheria toxin is a 58 kDa protein secreted by lysogenic strains of Corynebacterium diphtheriae. The toxin causes the disease diphtheria in humans by gaining entry into the cell cytoplasm and inhibiting protein Anti-Diphtheria toxin fragment A抗體synthesis. The mechanism of inhibition involves transfer of the ADP-ribose group of NAD to elongation factor-2 (EF-2), rendering EF-2 inactive. The catalysed reaction is as follows: NAD + + peptide diphthamide = nicotinamide + peptide N-(ADP-D-ribosyl)diphthamide The crystal structure of the diphtheria toxin homodimer has been determined to 2.5A resolution. The structure reveals a Y-shaped molecule of 3 domains, a catalytic domain (fragment A), whose fold is of the alpha + beta type; a transmembrane (TM) domain, which consists of 9 alpha-helices, 2 pairs of which may participate in pH-triggered membrane insertion and translocation; and a receptor-binding domain, which forms a flattened beta-barrel with a jelly-roll-like topology. The TM- and receptor binding-domains together constitute fragment B.
Also known as:
Diphtheria Toxin; DT; NAD(+)--diphthamide Anti-Diphtheria toxin fragment A抗體ADP-ribosyltransferase; Diphtheria toxin fragment A; DTX_CORBE.
Specificity:
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Rabbit Polyclonal IgG, affinity purified by Protein A.
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Reacts with: Corynephage beta.
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Immunogen: KLH conjugatedAnti-Diphtheria toxin fragment A抗體 synthetic peptide derived from human Diphther.
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Predicted Molecular Weight: 21kDa.
Storage:
Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
Not yet tested in other applications. Anti-Diphtheria toxin fragment A抗體
Optimal working dilutions must be determined by the end user.
Not yet tested in other applications. Anti-Diphtheria toxin fragment A抗體
Optimal working dilutions must be determined by the end user.
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