產(chǎn)品詳情
簡(jiǎn)單介紹：
Anti-DCTN1/DAP-150抗體產(chǎn)品質(zhì)量穩(wěn)定，實(shí)驗(yàn)效果明顯，貨期快，價(jià)格優(yōu)惠，歡迎垂詢訂購(gòu)！我公司長(zhǎng)期供應(yīng)**組化抗體、WB抗體、**組化試劑盒和抗體試驗(yàn)所需全部相關(guān)試劑、熒光標(biāo)記抗體、單克隆抗體、多克隆抗體、各種標(biāo)記的二抗IgG/IgM/IgD/IgA等科研實(shí)驗(yàn)抗體。Anti-DCTN1/DAP-150抗體用于**組化實(shí)驗(yàn),WB實(shí)驗(yàn),相應(yīng)的標(biāo)記抗體有HRP標(biāo)記抗體,FITC標(biāo)記,BIO等。
詳情介紹：
Rabbit Anti-DCTN1/DAP-150
Cat. Number:
Anti-DCTN1/DAP-150抗體KL-6929R
Quantity size:
0.2ml
Concentration:
1mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
Required for the cytoplasmic dynein-driven retrograde movement of vesicles and organelles along microtubules. Dynein-dynactin Anti-DCTN1/DAP-150抗體interaction is a key component of the mechanism of axonal transport of vesicles and organelles.
Tissue specificity; Brain.
Involvement in disease; Defects in DCTN1 are the cause of distal hereditary motor neuronopathy type 7B (HMN7B); also known as progressive lower motor neuron disease (PLMND). HMN7B is a neuromuscular disorder. Distal hereditary motor neuronopathies constitute a heterogeneous group of neuromuscular disorders caused by selective degeneration of motor neurons in the anterior horn of the spinal cord, without sensory deficit in the posterior horn. The overall clinical picture consists of a classical distal muscular atrophy syndrome in the legs without clinical sensory loss. The disease starts with weakness and wasting of distal muscles of the anterior tibial and peroneal compartments of the legs. Later on, weakness and atrophy may expand to the proximal Anti-DCTN1/DAP-150抗體muscles of the lower limbs and/or to the distal upper limbs.
Defects in DCTN1 are a cause of susceptibility to amyotrophic lateral sclerosis (ALS). ALS is a neurodegenerative disorder affecting upper and lower motor neurons, and resulting in fatal paralysis. Sensory abnormalities are absent. Death usually occurs within 2 to 5 years. The etiology is likely to be multifactorial, involving both genetic and environmental factors.
Defects in DCTN1 are the cause of Perry syndrome (PERRYS); also called parkinsonism with alveolar hypoventilation and mental depression. Perry syndrome is a neuropsychiatric disorder characterized by mental depression not responsive to antidepressant drugs or electroconvulsive therapy, sleep disturbances, exhaustion and marked weight loss. Parkinsonism develops later and respiratory failure occurred terminally.
Tissue specificity; Brain.
Involvement in disease; Defects in DCTN1 are the cause of distal hereditary motor neuronopathy type 7B (HMN7B); also known as progressive lower motor neuron disease (PLMND). HMN7B is a neuromuscular disorder. Distal hereditary motor neuronopathies constitute a heterogeneous group of neuromuscular disorders caused by selective degeneration of motor neurons in the anterior horn of the spinal cord, without sensory deficit in the posterior horn. The overall clinical picture consists of a classical distal muscular atrophy syndrome in the legs without clinical sensory loss. The disease starts with weakness and wasting of distal muscles of the anterior tibial and peroneal compartments of the legs. Later on, weakness and atrophy may expand to the proximal Anti-DCTN1/DAP-150抗體muscles of the lower limbs and/or to the distal upper limbs.
Defects in DCTN1 are a cause of susceptibility to amyotrophic lateral sclerosis (ALS). ALS is a neurodegenerative disorder affecting upper and lower motor neurons, and resulting in fatal paralysis. Sensory abnormalities are absent. Death usually occurs within 2 to 5 years. The etiology is likely to be multifactorial, involving both genetic and environmental factors.
Defects in DCTN1 are the cause of Perry syndrome (PERRYS); also called parkinsonism with alveolar hypoventilation and mental depression. Perry syndrome is a neuropsychiatric disorder characterized by mental depression not responsive to antidepressant drugs or electroconvulsive therapy, sleep disturbances, exhaustion and marked weight loss. Parkinsonism develops later and respiratory failure occurred terminally.
Also known as:
Alternative names150 kDa dyneinAnti-DCTN1/DAP-150抗體 associated polypeptide; 150 kDa dynein-associated polypeptide; DAP 150; DAP-150; DAP150; DCTN 1; DCTN1; DCTN1_HUMAN; DP 150; DP-150; DP150; Dynactin 1 (p150 Glued (Drosophila) homolog); Dynactin 1 (p150 glued homolog Drosophila); Dynactin 1; Dynactin subunit 1; Dynactin1; HMN7B; P135; p150 Glued (Drosophila) homolog; p150 glued; p150 glued homolog; p150(GLUED) DROSOPHILA HOMOLOG OF; p150-glued; p150glued.
Specificity:
●
Rabbit Polyclonal IgG, affinity purified by Protein A.
●
Reacts with: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, .
●
Immunogen: KLH conjugated synthetic peptide derived from human DCTN1/Dy.
●
Predicted Molecular Weight: 142kDa.
Storage:
Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
Not yet tested in other applications. Anti-DCTN1/DAP-150抗體
Optimal working dilutions must be determined by the end user.
Not yet tested in other applications. Anti-DCTN1/DAP-150抗體
Optimal working dilutions must be determined by the end user.
kl117Ra01 胞外超氧化物歧化酶(SOD3)多克隆抗體 Polyclonal Antibody to Superoxide Dismutase 3, Extracellular (SOD3)
kl083Mu01 線粒體超氧化物歧化酶(SOD2)多克隆抗體 Polyclonal Antibody to Superoxide Dismutase 2, Mitochondrial (SOD2)
kl083Ra01 線粒體超氧化物歧化酶(SOD2)多克隆抗體 Polyclonal Antibody to Superoxide Dismutase 2, Mitochondrial (SOD2)
kl960Hu01 超氧化物歧化酶1(SOD1)多克隆抗體 Polyclonal Antibody to Superoxide Dismutase 1, Soluble (SOD1)
kl960Mu01 超氧化物歧化酶1(SOD1)多克隆抗體 Polyclonal Antibody to Superoxide Dismutase 1, Soluble (SOD1)
kl960Ra01 超氧化物歧化酶1(SOD1)多克隆抗體 Polyclonal Antibody to Superoxide Dismutase 1, Soluble (SOD1)
kl596Hu01 銅伴侶超氧化物歧化酶(SOD4)多克隆抗體 Polyclonal Antibody to Superoxide Dismutase, Copper Chaperone (SOD4)
kl596Mu01 銅伴侶超氧化物歧化酶(SOD4)多克隆抗體 Polyclonal Antibody to Superoxide Dismutase, Copper Chaperone (SOD4)
kl596Ra01 銅伴侶超氧化物歧化酶(SOD4)多克隆抗體 Polyclonal Antibody to Superoxide Dismutase, Copper Chaperone (SOD4)
kl260Hu01 β2-微球蛋白(β2M)多克隆抗體 Polyclonal Antibody to Beta-2-Microglobulin (b2M)
kl260Mu01 β2-微球蛋白(β2M)多克隆抗體 Polyclonal Antibody to Beta-2-Microglobulin (b2M)
kl260Ra01 β2-微球蛋白(β2M)多克隆抗體 Polyclonal Antibody to Beta-2-Microglobulin (b2M)
kl812Hu01 胰淀素(IAPP)多克隆抗體 Polyclonal Antibody to Islet Amyloid Polypeptide (IAPP)
kl812Mu01 胰淀素(IAPP)多克隆抗體 Polyclonal Antibody to Islet Amyloid Polypeptide (IAPP)
kl812Ra01 胰淀素(IAPP)多克隆抗體 Polyclonal Antibody to Islet Amyloid Polypeptide (IAPP)
kl640Hu01 鈣調(diào)素(CAM)多克隆抗體 Polyclonal Antibody to Calmodulin (CAM)
kl640Ra01 鈣調(diào)素(CAM)多克隆抗體 Polyclonal Antibody to Calmodulin (CAM)
kl656Hu01 三葉因子3(TFF3)多克隆抗體 Polyclonal Antibody to Trefoil Factor 3, Intestinal (TFF3)
kl656Mu01 三葉因子3(TFF3)多克隆抗體 Polyclonal Antibody to Trefoil Factor 3, Intestinal (TFF3)
kl656Ra01 三葉因子3(TFF3)多克隆抗體 Polyclonal Antibody to Trefoil Factor 3, Intestinal (TFF3)
kl541Hu01 腦鈉素(BNP)多克隆抗體 Polyclonal Antibody to Brain Natriuretic Peptide (BNP)
