產品詳情
簡單介紹：
Anti-phospho-ATF2 (Thr73 / Thr55)抗體產品質量穩定，實驗效果明顯，貨期快，價格優惠，歡迎垂詢訂購！我公司長期供應**組化抗體、WB抗體、**組化試劑盒和抗體試驗所需全部相關試劑、熒光標記抗體、單克隆抗體、多克隆抗體、各種標記的二抗IgG/IgM/IgD/IgA等科研實驗抗體。Anti-phospho-ATF2 (Thr73 / Thr55)抗體用于**組化實驗,WB實驗,相應的標記抗體有HRP標記抗體,FITC標記,BIO等。
詳情介紹：
Rabbit Anti-phospho-ATF2 (Thr73 / Thr55)
Cat. Number:
Anti-phospho-ATF2 (Thr73 / Thr55)抗體KL-12539R
Quantity size:
0.1ml
Concentration:
1mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
ATF2 is a member of the ATF/CREB family of basic region leucine zipper DNA binding proteins that regulates transcription Anti-phospho-ATF2 (Thr73 / Thr55)抗體by binding to a consensus cAMP response element (CRE) in the promoter of various viral and cellular genes. Many of these genes are important in cell growth and differentiation, and in stress and immune responses. ATF2 is a nuclear protein that binds DNA as a dimer and can form dimers with members of the ATF/CREB and Jun/Fos families. It is a stronger activator as a heterodimer with cJun than as a homodimer. Several isoforms of ATF2 arise by differential splicing. The stable native full length ATF2 is transcriptionally inactive as a result of an inhibitory direct intramolecular interaction of its carboxy terminal DNA binding domain with the amino terminal transactivation domain. Following dimerization ATF2 becomes a short lived protein that undergoes ubiquitination and proteolysis, seemingly in a protein phosphatase-dependent mechanism. Stimulation of the transcriptional activity of ATF2 occurs following cellular stress induced by several genotoxic agents, inflammatory cytokines, and UV irradiation. This activation requires phosphorylation of two threonine residues in ATF2 by both JNK/SAP kinase and p38 MAP kinase. ATF2 is abundantly expressed in brain.
Also known as:
Anti-phospho-ATF2 (Thr73 / Thr55)抗體phospho-ATF2 (Thr73)human; phospho-ATF2 (Thr55)mouse; ATF2 (phospho T73 + T55); p-ATF2 (phospho T73 + T55); p-ATF2 (phospho T73 + T55); CREB 2; HB 16; Activating Transcription Factor 2; ATF 2; Atf-2; ATF2 protein; cAMP Response Element Binding Protein 2; cAMP response element binding protein CRE BP1; cAMP-dependent transcription factor ATF-2; cAMP-responsive element-binding protein 2; CRE BP1; CRE-BP; CREB 2; CREB2; CREBP1; Cyclic AMP dependent transcription factor ATF 2; Cyclic AMP-responsive; ATF2_HUMAN.
Specificity:
●
Rabbit Polyclonal IgG, affinity purified by Protein A.
●
Reacts with: Human, Mouse, Rat, .
●
Immunogen: KLH conjugated synthesised phosphopeptide derived from human ATF2 around the phosphorylation site of Thr73 + Thr55.
●
Predicted Molecular Weight: 52kDa.
Storage:
Shipped Anti-phospho-ATF2 (Thr73 / Thr55)抗體at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
Not yet tested in other applications.
OptimalAnti-phospho-ATF2 (Thr73 / Thr55)抗體 working dilutions must be determined by the end user.
Not yet tested in other applications.
OptimalAnti-phospho-ATF2 (Thr73 / Thr55)抗體 working dilutions must be determined by the end user.
kl798Ga01 低氧誘導因子1α(HIF1α)多克隆抗體 Polyclonal Antibody to Hypoxia Inducible Factor 1 Alpha (HIF1a)
kl840Bo01 凝血因子Ⅸ(F9)多克隆抗體 Polyclonal Antibody to Coagulation Factor IX (F9)
kl896Ca01 半胱氨酸蛋白酶抑制劑3(CST3)多克隆抗體 Polyclonal Antibody to Cystatin 3 (CST3)
kl309Bo01 多效生長因子(PTN)多克隆抗體 Polyclonal Antibody to Pleiotrophin (PTN)
kl743Bo01 信號傳導轉錄激活因子3(STAT3)多克隆抗體 Polyclonal Antibody to Signal Transducer And Activator Of Transcription 3 (STAT3)
kl750Ca01 腫瘤壞死因子配體超家族成員13(TNFSF13)多克隆抗體 Polyclonal Antibody to Tumor Necrosis Factor Ligand Superfamily, Member 13 (TNFSF13)
kl825Hu01 核因子κB2(NFκB2)多克隆抗體 Polyclonal Antibody to Nuclear Factor Kappa B2 (NFkB2)
kl020Bo01 S100鈣結合蛋白A4(S100A4)多克隆抗體 Polyclonal Antibody to S100 Calcium Binding Protein A4 (S100A4)
kl030Ra01 腦型肌酸激酶(CKB)多克隆抗體 Polyclonal Antibody to Creatine Kinase, Brain (CKB)
kl046Ra01 S100鈣結合蛋白A10(S100A10)多克隆抗體 Polyclonal Antibody to S100 Calcium Binding Protein A10 (S100A10)
kl050Ra01 高遷移率族AT Hook蛋白1(HMGA1)多克隆抗體 Polyclonal Antibody to High Mobility Group AT Hook Protein 1 (HMGA1)
kl071Hu01 干擾素誘導T-細胞α亞族趨化劑(ITαC)多克隆抗體 Polyclonal Antibody to Interferon Inducible T-Cell Alpha Chemoattractant (ITaC)
kl091Hu01 巨噬細胞炎性蛋白4α(MIP4α)多克隆抗體 Polyclonal Antibody to Macrophage Inflammatory Protein 4 Alpha (MIP4a)
kl110Mu01 生長分化因子5(GDF5)多克隆抗體 Polyclonal Antibody to Growth Differentiation Factor 5 (GDF5)
kl128Ga01 Gremlin 1蛋白(GREM1)多克隆抗體 Polyclonal Antibody to Gremlin 1 (GREM1)
kl130Ca01 頭蛋白(NOG)多克隆抗體 Polyclonal Antibody to Noggin (NOG)
kl130Ga01 頭蛋白(NOG)多克隆抗體 Polyclonal Antibody to Noggin (NOG)
kl141Hu01 Ⅳ型膠原α5(COL4α5)多克隆抗體 Polyclonal Antibody to Collagen Type IV Alpha 5 (COL4a5)
kl220Ra01 博來霉素水解酶(BLMH)多克隆抗體 Polyclonal Antibody to Bleomycin Hydrolase (BLMH)
