產品詳情
簡單介紹：
Anti-ADAM20抗體產品質量穩定，實驗效果明顯，貨期快，價格優惠，歡迎垂詢訂購！我公司長期供應**組化抗體、WB抗體、**組化試劑盒和抗體試驗所需全部相關試劑、熒光標記抗體、單克隆抗體、多克隆抗體、各種標記的二抗IgG/IgM/IgD/IgA等科研實驗抗體。Anti-ADAM20抗體用于**組化實驗,WB實驗,相應的標記抗體有HRP標記抗體,FITC標記,BIO等。
詳情介紹：
Rabbit Anti-ADAM20
Cat. Number:
Anti-ADAM20抗體KL-5852R
Quantity size:
0.2ml
Concentration:
1mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
ADAM20 was first cloned from a human testis library as a protein with homology to the fertilins (ADAMs 1, 2). Anti-ADAM20抗體ADAM20 message was seen predominantly in testis, but also at lower levels in placenta and B-cells. ADAM20 is closely related to ADAM21 (61% identical), ADAM29 (52% identical), and the testases (49-46% identical). ADAM20 contains the canonical HExxHxxxxxH zinc metalloproteinase motif, and the initial partial sequence of ADAM21 contained a non-functional catalytic site, making it tempting to speculate that ADAM20 and ADAM21 are orthologs to ADAMs 1&2. Later, a full-length ADAM21 sequence demonstrated a functional catalytic domain, but it may still be that the catalytically dead form of ADAM21 is expressed and functions as a fettilin. A member of the metalloproteinase family containing disintegrin-like domains (ADAMs) the function of ADAM20 is still poorly understood. Other ADAMs family members (ADAM10, ADAM17) have been more thoroughly studied, and are known to play key roles in inflammation, growth factor maturation and release, and a wide range of other functions. The full length ADAM20 sequence codes for a 726 amino acid protein, with a predicted mass is 81.711 kD. The sequence containing a Type-I transmembrane domain, metalloproteinase domain, cystein-rich domain, and a short cytoplasmic domain. Unlike many of the other ADAMs proteases, ADAM20 does not appear to contain a furin cleavage site.
Also known as:
A disintegrinAnti-ADAM20抗體 and metalloproteinase domain 20; A disintegrin and metalloproteinase domain 20 preproprotein; ADA20_HUMAN; ADAM 20; ADAM metallopeptidase domain 20; ADAM20; Disintegrin and metalloproteinase domain-containing protein 20; EC 3.4.24.; OTTHUMP00000236151.
Specificity:
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Rabbit Polyclonal IgG, affinity purified by Protein A.
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Reacts with: Human, .
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Immunogen: KLH conjugated synthetic peptide derived from human ADAM20.
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Predicted Molecular Weight: 52kDa.
Storage:
Shipped at 4℃, Anti-ADAM20抗體Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
Not yet tested in other applications.
Optimal working Anti-ADAM20抗體dilutions must be determined by the end user.
Not yet tested in other applications.
Optimal working Anti-ADAM20抗體dilutions must be determined by the end user.
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