IMMUDEX

Unravel ImmunitySolutions for improved T-cell immune monitoring within immuno-oncology, transplantation, autoimmunity and infectious disease.Dextramer technologies for first class detection of disease-specific T cells.

IMMUDEX

MHC I Dextramer

MHC II Dextramer

CD1d Dextramer

dCODE Dextramer for NGS

Klickmer

GMP products

Dextramer CMV Kit (IVD)

Latest News

Job Opportunity: Sales Territory Manager USA West Coast

Job Opportunity: Sales Territory Manager (Europe)

Antigen-Specific T Cells can be measured accurately: MHC Proficiency Panel Report out now

Measure ImmunityThe MHC Multimer assay provides a simple and accurate enumeration of antigen-specific T cells.

IMMUDEX News

Job Opening: Market Development Manager US West Coast ??

Immudex Nominated for the Gazelle Company Awards 2018 ??

September 2018,  Immudex partners with 10x Genomics to enhance applications of its dCODE? Dextramer® Technology ??

March 2018, the dCODE Dextramer is launched  ??

January 2018, the Dextramer CMV Kit - IVD is available in the USA ??

August 2017, The MHC Multimer Proficiency Panel report 2017 is available ??

February 20th, 2017 Helene K?hler Hjenner is the new CEO of Immudex ??

Next-level success in managing the world's most prevalent virus ??

November 5th, 2013 JPT-Immudex Partnership Agreement ??

April 23th, 2013, Immudex becomes the provider of MHC Multimer and Elispot Proficiency Panels service ??

November 29th, 2011: DANISH, Article in B?rsen: Dako-knopskud ser milliardpotentiale ??

November 24th, 2011: ENGLISH, Press Release, Ernst & Young: Immudex wins Life Sciences category Entrepreneur Of The Year 2011 ??

December 8th, 2010: DANISH,Article in B?rsen: Dako-arvinger satser millioner p? biotek ??

October 9th, 2009: ENGLISH, Immudex, a new spin-out from Dako ??

October 9th, 2009: DANISH,Article in B?rsen: Virksomheder overser gyldne knopskydninger ??

IMMUDEX

Efficient detection of antigen-specific T cells depends on sensitive, high quality reagents. 

The MHC Dextramer^® reagents consists of a dextran polymer backbone carrying an optimized number of MHC molecules and fluorochromes. The dextran polymer stabilizes the conformation of the attached MHC-peptide complexes and fluorochromes, making MHC Dextramer reagents highly stable reagents.

MHC Dextramer reagents carry more MHC molecules and more fluorochromes than conventional MHC multimers. This increases their avidity for the specific T cell and enhances their staining intensity, thereby increasing resolution and ensures minimal background staining.

Dextramer reagents are particularly efficient in the detection of T cells carrying T-cell receptors with low affinity for MHC-peptide ??. This enable discovery of T-cell specificities that not previously have been investigated and can facilitate a new understanding of T-cell immunity.

Every single product is produced to the highest standards using purified single components, and quality-controlled for fluorescence and correct folding of MHC-peptide complexes. This ensures high reproducibility and minimal lot-to-lot variations.

Fields of application

• Monitoring antigen-specific T-cell responses
  • Vaccine development
  • Immunotherapeutic development
  • Clinical trials
• Determination of antigen-specific immune status 
  • Transplantation
  • Immunodeficient
  • Patients receiving immunosuppressive drugs
• Profiling T-cell responses
  • Infectious disease
  • Cancer
  • Autoimmunity and other malignancies
• Immunological research
  • Detection of antigen-specific T-cell responses 
  • Confirmation of T cell clone specificity
  • Validation of T cell immunotherapeutics