產品詳情
簡單介紹：
Anti-KLK7抗體產品質量穩定，實驗效果明顯，貨期快，價格優惠，歡迎垂詢訂購！我公司長期供應**組化抗體、WB抗體、**組化試劑盒和抗體試驗所需全部相關試劑、熒光標記抗體、單克隆抗體、多克隆抗體、各種標記的二抗IgG/IgM/IgD/IgA等科研實驗抗體。Anti-KLK7抗體用于**組化實驗,WB實驗,相應的標記抗體有HRP標記抗體,FITC標記,BIO等。
詳情介紹：
Rabbit Anti-KLK7
Cat. Number:
Anti-KLK7抗體KL-1966R
Quantity size:
0.2ml
Concentration:
1mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
The human tissue Kallikrein gene family encodes 15 serine proteases. All Kallikreins share structural similarities including cysteine residues, a catalytic triad of His, Asp, and Ser residues, typically five coding exons and varied intron phases. Kallikreins are predominantly secreted as inactive zymogens prior to activation by cleavage of an N-terminal peptide and all function extracellularly. Kallikreins can be activated autocatalytically, via Anti-KLK7抗體other Kallikreins, or additional proteases. While structurally similar, Kallikrein family members have distinct functions and have key roles in many physiological and pathological processes. Many human tissue Kallikreins also show promise as cancer biomarkers, which may facilitate earlier detection and characterization of many forms of cancer.
Kallikrein 7, also known as stratum corneum chymotryptic enzyme (SCCE) and PRSS6, is a chymotrypsin-like serine proteinase. Originally described from human skin as a serine protease involved in shedding of skin cells andAnti-KLK7抗體 remodeling if the skin, SCCE was later identified as Kallikrein 7. Kallikrein 7 is found at the highest levels in the skin, often complexed with the endogenous serpins SLPI or elafin and kallikrein 7 can be found complexed to a number of different proteinase inhibitors. In addition to skin, Kallikrein 7 has been found in the kidney, esophagus, neuronal tissues, amniotic fluid, saliva, breast milk, urine, synovial fluid, seminal plasma and serum. Kallikrein 7 has been reported to be decreased in the CSF of Alzheimer's patients and message levels of KLK7 were decreased in adenocarcinoma. In skin, overexpression of hK7 has been shown to cause a form of dermatitis and in psoriasis hK7 is expressed in higher levels than controls. The skin adhesive proteins corneodesmosin and desmocollin 1 have been reported to be substrates of Kallikrein 7, as is interleukin 1 and the insulin B-chain.
Kallikrein 7, also known as stratum corneum chymotryptic enzyme (SCCE) and PRSS6, is a chymotrypsin-like serine proteinase. Originally described from human skin as a serine protease involved in shedding of skin cells andAnti-KLK7抗體 remodeling if the skin, SCCE was later identified as Kallikrein 7. Kallikrein 7 is found at the highest levels in the skin, often complexed with the endogenous serpins SLPI or elafin and kallikrein 7 can be found complexed to a number of different proteinase inhibitors. In addition to skin, Kallikrein 7 has been found in the kidney, esophagus, neuronal tissues, amniotic fluid, saliva, breast milk, urine, synovial fluid, seminal plasma and serum. Kallikrein 7 has been reported to be decreased in the CSF of Alzheimer's patients and message levels of KLK7 were decreased in adenocarcinoma. In skin, overexpression of hK7 has been shown to cause a form of dermatitis and in psoriasis hK7 is expressed in higher levels than controls. The skin adhesive proteins corneodesmosin and desmocollin 1 have been reported to be substrates of Kallikrein 7, as is interleukin 1 and the insulin B-chain.
Also known as:
Kallikrein 7; Chymotryptic stratum corneum; hK 7; hK7; hSCCE; hSCCE; Kallikrein 7 (chymotryptic stratum corneum); Kallikrein related peptidase 7; Kallikrein-7; Kallikrein7; KLK 7; Klk7; KLK7_HUMAN; Protease serine 6; PRSS 6; PRSS6; SCCE; Serine protease 6; Signal protein; Stratum corneum chymotryptic enzyme; Anti-KLK7抗體Stratum corneum chymotryptic enzyme.
Specificity:
●
Rabbit Polyclonal IgG, affinity purified by Protein A.
●
Reacts with: Human, Mouse, Rat, Dog, Pig, Cow, .
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Immunogen: KLH conjugated synthetic peptide derived from human KLK7.
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Predicted Molecular Weight: 24kDa.
Storage:
Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
Not yet tested in other applications. Anti-KLK7抗體
Optimal working dilutions must be determined by the end user.
Not yet tested in other applications. Anti-KLK7抗體
Optimal working dilutions must be determined by the end user.
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kl128Ra01 組織金屬蛋白酶抑制因子2(TIMP2)多克隆抗體 Polyclonal Antibody to Tissue Inhibitors Of Metalloproteinase 2 (TIMP2)
kl128Rb51 組織金屬蛋白酶抑制因子2(TIMP2)多克隆抗體 Polyclonal Antibody to Tissue Inhibitors Of Metalloproteinase 2 (TIMP2)
kl129Bo01 組織金屬蛋白酶抑制因子3(TIMP3)多克隆抗體 Polyclonal Antibody to Tissue Inhibitors Of Metalloproteinase 3 (TIMP3)
kl129Cp01 組織金屬蛋白酶抑制因子3(TIMP3)多克隆抗體 Polyclonal Antibody to Tissue Inhibitors Of Metalloproteinase 3 (TIMP3)
kl129Eq01 組織金屬蛋白酶抑制因子3(TIMP3)多克隆抗體 Polyclonal Antibody to Tissue Inhibitors Of Metalloproteinase 3 (TIMP3)
kl129Fi01 組織金屬蛋白酶抑制因子3(TIMP3)多克隆抗體 Polyclonal Antibody to Tissue Inhibitors Of Metalloproteinase 3 (TIMP3)
kl129Ga01 組織金屬蛋白酶抑制因子3(TIMP3)多克隆抗體 Polyclonal Antibody to Tissue Inhibitors Of Metalloproteinase 3 (TIMP3)
kl129Hu01 組織金屬蛋白酶抑制因子3(TIMP3)多克隆抗體 Polyclonal Antibody to Tissue Inhibitors Of Metalloproteinase 3 (TIMP3)
kl129Mu01 組織金屬蛋白酶抑制因子3(TIMP3)多克隆抗體 Polyclonal Antibody to Tissue Inhibitors Of Metalloproteinase 3 (TIMP3)
kl129Po01 組織金屬蛋白酶抑制因子3(TIMP3)多克隆抗體 Polyclonal Antibody to Tissue Inhibitors Of Metalloproteinase 3 (TIMP3)
kl129Ra01 組織金屬蛋白酶抑制因子3(TIMP3)多克隆抗體 Polyclonal Antibody to Tissue Inhibitors Of Metalloproteinase 3 (TIMP3)
kl129Rb51 組織金屬蛋白酶抑制因子3(TIMP3)多克隆抗體 Polyclonal Antibody to Tissue Inhibitors Of Metalloproteinase 3 (TIMP3)
kl129Si01 組織金屬蛋白酶抑制因子3(TIMP3)多克隆抗體 Polyclonal Antibody to Tissue Inhibitors Of Metalloproteinase 3 (TIMP3)
kl130Bo01 組織金屬蛋白酶抑制因子4(TIMP4)多克隆抗體 Polyclonal Antibody to Tissue Inhibitors Of Metalloproteinase 4 (TIMP4)
kl130Hu01 組織金屬蛋白酶抑制因子4(TIMP4)多克隆抗體 Polyclonal Antibody to Tissue Inhibitors Of Metalloproteinase 4 (TIMP4)
