產(chǎn)品詳情
簡單介紹：
Anti-HCA57抗體產(chǎn)品質(zhì)量穩(wěn)定，實驗效果明顯，貨期快，價格優(yōu)惠，歡迎垂詢訂購！我公司長期供應(yīng)**組化抗體、WB抗體、**組化試劑盒和抗體試驗所需全部相關(guān)試劑、熒光標(biāo)記抗體、單克隆抗體、多克隆抗體、各種標(biāo)記的二抗IgG/IgM/IgD/IgA等科研實驗抗體。Anti-HCA57抗體用于**組化實驗,WB實驗,相應(yīng)的標(biāo)記抗體有HRP標(biāo)記抗體,FITC標(biāo)記,BIO等。
詳情介紹：
Rabbit Anti-HCA57
Cat. Number:
Anti-HCA57抗體KL-7645R
Quantity size:
0.2ml
Concentration:
1mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
TID1 is a human homolog of the Drosophila tumor suppressor lethal tumerous imaginal discs and encodes two mitochondrial matrixAnti-HCA57抗體 localized splice variants of human Tid1 designated hTid1S and hTid1L. These proteins are the conserved members of the DnaJ family of proteins which act as cochaperons for mitochondrial Hsp70. They contain a conserved tetrahedrical J domain which binds to Hsp70 chaperones and activates their ATPase activity. Expression of hTid1L increases apoptosis induced by DNA damaging agents as mitomycin C and TNF alpha. A J domain mutant of hTid1L can dominantly suppress apoptosis and in sharp contrast the J domain mutant of hTid1S increases apoptosis. Expression of hTid1S and hTid1L affects cytochrome c release from the mitochondria and caspase 3 activation, while activation of caspase 8 is unaffected. It is strongly suggested that these two splice variants exert their anti and pro apoptotic effects through discrete substrates and activities. Hence the relative abundance of these proteins or their substrates may allow the mitochondria to dampen or enhance the apoptotic signals.
Also known as:
DnaJ (Hsp40) homolog subfamily A Anti-HCA57抗體member 3; DnaJ homolog subfamily A member 3 mitochondrial precursor; DnaJ protein Tid 1; DnaJ protein Tid1; HCA57; Hepatocellular carcinoma associated antigen 57; Highly similar to HYPOTHETICAL 105.9 KD PROTEIN F22B7.5 IN CHROMOSOME; hTid 1; hTid1; III [Caenorhabditis elegans]; TID1; Tumorous imaginal discs (Drosophila) homolog; Tumorous imaginal discs protein Tid56 homolog; DNJA3_HUMAN.
Specificity:
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Rabbit Polyclonal IgG, affinity purified by Anti-HCA57抗體Protein A.
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Reacts with: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep, .
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Immunogen: KLH conjugated synthetic peptide derived from human TID1/HCA.
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Predicted Molecular Weight: 52kDa.
Storage:
Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
Not yet tested in other applications. Anti-HCA57抗體
Optimal working dilutions must be determined by the end user.kl242Mu01 核仁素(NCL)多克隆抗體 Polyclonal Antibody to Nucleolin (NCL)
kl243Hu01 拓?fù)洚悩?gòu)酶Ⅰ(TOP1)多克隆抗體 Polyclonal Antibody to Topoisomerase I (TOP1)
kl246Mu01 磷酸肌醇依賴性蛋白激酶1(PDPK1)多克隆抗體 Polyclonal Antibody to Phosphoinositide Dependent Protein Kinase 1 (PDPK1)
kl257Hu01 62kDa核孔蛋白(NUP62)多克隆抗體 Polyclonal Antibody to Nucleoporin 62kDa (NUP62)
kl260Hu01 融合蛋白(FUS)多克隆抗體 Polyclonal Antibody to Fusion (FUS)
kl260Mu01 融合蛋白(FUS)多克隆抗體 Polyclonal Antibody to Fusion (FUS)
kl262Hu01 緊密連接蛋白1(TJP1)多克隆抗體 Polyclonal Antibody to Tight Junction Protein 1 (TJP1)
kl268Hu01 11-β-羥基類固醇脫氫酶1(HSD11β1)多克隆抗體 Polyclonal Antibody to 11-Beta-Hydroxysteroid Dehydrogenase Type 1 (HSD11b1)
kl268Ra01 11-β-羥基類固醇脫氫酶1(HSD11β1)多克隆抗體 Polyclonal Antibody to 11-Beta-Hydroxysteroid Dehydrogenase Type 1 (HSD11b1)
kl270Hu01 7-脫氫膽固醇還原酶(DHCR7)多克隆抗體 Polyclonal Antibody to 7-Dehydrocholesterol Reductase (DHCR7)
kl276Hu01 氨基?；?(ACY1)多克隆抗體 Polyclonal Antibody to Aminoacylase 1 (ACY1)
kl281Hu01 腺苷激酶(ADK)多克隆抗體 Polyclonal Antibody to Adenosine Kinase (ADK)
kl284Hu01 α白蛋白(AFM)多克隆抗體 Polyclonal Antibody to Afamin (AFM)
kl284Mu01 α白蛋白(AFM)多克隆抗體 Polyclonal Antibody to Afamin (AFM)
kl285Hu01 前梯度蛋白2(AGR2)多克隆抗體 Polyclonal Antibody to Anterior Gradient Protein 2 (AGR2)
kl288Hu01 同種異體移植炎癥因子1(AIF1)多克隆抗體 Polyclonal Antibody to Allograft Inflammatory Factor 1 (AIF1)
kl288Mu01 同種異體移植炎癥因子1(AIF1)多克隆抗體 Polyclonal Antibody to Allograft Inflammatory Factor 1 (AIF1)
Not yet tested in other applications. Anti-HCA57抗體
Optimal working dilutions must be determined by the end user.kl242Mu01 核仁素(NCL)多克隆抗體 Polyclonal Antibody to Nucleolin (NCL)
kl243Hu01 拓?fù)洚悩?gòu)酶Ⅰ(TOP1)多克隆抗體 Polyclonal Antibody to Topoisomerase I (TOP1)
kl246Mu01 磷酸肌醇依賴性蛋白激酶1(PDPK1)多克隆抗體 Polyclonal Antibody to Phosphoinositide Dependent Protein Kinase 1 (PDPK1)
kl257Hu01 62kDa核孔蛋白(NUP62)多克隆抗體 Polyclonal Antibody to Nucleoporin 62kDa (NUP62)
kl260Hu01 融合蛋白(FUS)多克隆抗體 Polyclonal Antibody to Fusion (FUS)
kl260Mu01 融合蛋白(FUS)多克隆抗體 Polyclonal Antibody to Fusion (FUS)
kl262Hu01 緊密連接蛋白1(TJP1)多克隆抗體 Polyclonal Antibody to Tight Junction Protein 1 (TJP1)
kl268Hu01 11-β-羥基類固醇脫氫酶1(HSD11β1)多克隆抗體 Polyclonal Antibody to 11-Beta-Hydroxysteroid Dehydrogenase Type 1 (HSD11b1)
kl268Ra01 11-β-羥基類固醇脫氫酶1(HSD11β1)多克隆抗體 Polyclonal Antibody to 11-Beta-Hydroxysteroid Dehydrogenase Type 1 (HSD11b1)
kl270Hu01 7-脫氫膽固醇還原酶(DHCR7)多克隆抗體 Polyclonal Antibody to 7-Dehydrocholesterol Reductase (DHCR7)
kl276Hu01 氨基?；?(ACY1)多克隆抗體 Polyclonal Antibody to Aminoacylase 1 (ACY1)
kl281Hu01 腺苷激酶(ADK)多克隆抗體 Polyclonal Antibody to Adenosine Kinase (ADK)
kl284Hu01 α白蛋白(AFM)多克隆抗體 Polyclonal Antibody to Afamin (AFM)
kl284Mu01 α白蛋白(AFM)多克隆抗體 Polyclonal Antibody to Afamin (AFM)
kl285Hu01 前梯度蛋白2(AGR2)多克隆抗體 Polyclonal Antibody to Anterior Gradient Protein 2 (AGR2)
kl288Hu01 同種異體移植炎癥因子1(AIF1)多克隆抗體 Polyclonal Antibody to Allograft Inflammatory Factor 1 (AIF1)
kl288Mu01 同種異體移植炎癥因子1(AIF1)多克隆抗體 Polyclonal Antibody to Allograft Inflammatory Factor 1 (AIF1)
