產品詳情
簡單介紹:
Anti-G protein beta subunit like抗體產品質量穩定,實驗效果明顯,貨期快,價格優惠,歡迎垂詢訂購!我公司長期供應**組化抗體、WB抗體、**組化試劑盒和抗體試驗所需全部相關試劑、熒光標記抗體、單克隆抗體、多克隆抗體、各種標記的二抗IgG/IgM/IgD/IgA等科研實驗抗體。Anti-G protein beta subunit like抗體用于**組化實驗,WB實驗,相應的標記抗體有HRP標記抗體,FITC標記,BIO等。
詳情介紹:
Rabbit Anti-G protein beta subunit like
Cat. Number:
Anti-G protein beta subunit like抗體KL-8161R
Quantity size:
0.2ml
Concentration:
1mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
Subunit of both mTORC1 and mTORC2, which regulates cell growth and survival in response to nutrient and hormonal signals. mTORC1 is activated in response to growth factors or amino-acids. Growth factor-stimulated mTORC1Anti-G protein beta subunit like抗體 activation involves a AKT1-mediated phosphorylation of TSC1-TSC2, which leads to the activation of the RHEB GTPase that potently activates the protein kinase activity of mTORC1. Amino-acid-signaling to mTORC1 requires its relocalization to the lysosomes mediated by the Ragulator complex and the Rag GTPases. Activated mTORC1 up-regulates protein synthesis by phosphorylating key regulators of mRNA translation and ribosome synthesis. mTORC1 phosphorylates EIF4EBP1 and releases it from inhibiting the elongation initiation factor 4E (eiF4E). mTORC1 phosphorylates and activates S6K1 at 'Thr-389', which then promotes protein synthesis by phosphorylating PDCD4 and targeting it for degradation.
Tissue specificity:Broadly expressed, Anti-G protein beta subunit like抗體with highest levels in skeletal muscle, heart and kidney.
Tissue specificity:Broadly expressed, Anti-G protein beta subunit like抗體with highest levels in skeletal muscle, heart and kidney.
Also known as:
G protein beta subunit like; G protein beta subunit-like; Gable; GBL; GBL protein; LST8_HUMAN; Mammalian lethal with SEC13 protein 8;Anti-G protein beta subunit like抗體 MGC111011; mLST8; Protein GbetaL; Target of rapamycin complex subunit LST8; TORC subunit LST8.
Specificity:
●
Rabbit Polyclonal IgG, affinity purified by Protein A.
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Reacts with: Human, Mouse, Rat, Dog, Pig, Cow, Sheep, .
●
Immunogen: KLH conjugated synthetic peptide derived from human G protei.
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Predicted Molecular Weight: 36kDa.
Storage:
Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
Not yet tested in other applications. Anti-G protein beta subunit like抗體
Optimal working dilutions must be determined by the end user.
Not yet tested in other applications. Anti-G protein beta subunit like抗體
Optimal working dilutions must be determined by the end user.
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