產(chǎn)品詳情
簡(jiǎn)單介紹：
Anti-Epsin 3抗體產(chǎn)品質(zhì)量穩(wěn)定，實(shí)驗(yàn)效果明顯，貨期快，價(jià)格優(yōu)惠，歡迎垂詢訂購(gòu)！我公司長(zhǎng)期供應(yīng)**組化抗體、WB抗體、**組化試劑盒和抗體試驗(yàn)所需全部相關(guān)試劑、熒光標(biāo)記抗體、單克隆抗體、多克隆抗體、各種標(biāo)記的二抗IgG/IgM/IgD/IgA等科研實(shí)驗(yàn)抗體。Anti-Epsin 3抗體用于**組化實(shí)驗(yàn),WB實(shí)驗(yàn),相應(yīng)的標(biāo)記抗體有HRP標(biāo)記抗體,FITC標(biāo)記,BIO等。
詳情介紹：
Rabbit Anti-Epsin 3
Cat. Number:
Anti-Epsin 3抗體KL-14613R
Quantity size:
0.2ml
Concentration:
1mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
Epsin 3 is a 632 amino acid member of the epsin protein family. Epsin 3 localizes mainly to the perinuclear region of the nucleus and in clathrin-coated vesicles close to the cell periphery. Epsin 3 is expressed in migrating keratinocytes from wounded skin, but not in normal skin or differentiating keratinocytes. Epsin 3 contains oneAnti-Epsin 3抗體 ENTH (epsin N-terminal homology) domain and two UIM (ubiquitin-interacting motif) repeats and is expressed as two isoforms produced by alternative splicing. The gene that encodes epsin 3 maps to human chromosome 17, which comprises over 2.5% of the human genome and encodes over 1,200 genes. Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1. Tumor suppressor p53 is necessary for maintenance of cellular genetic integrity by moderating cell fate through DNA repair versus cell death. Malfunction or loss of p53 expression is associated with malignant cell growth and Li-Fraumeni syndrome. Like p53, BRCA1 is directly involved in DNA repair, specifically it is recognized as a genetic determinant of early onset breast cancer and predisposition to cancers of the ovary, colon, prostate gland and fallopian tubes.
Also known as:
EPN3 EPN 3; EPN3_HUMAN; Anti-Epsin 3抗體EPS 15 interacting protein 3; Epsin-3; Epsin3; FLJ20778; MGC129899.
Specificity:
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Rabbit Polyclonal IgG, affinity purified by Protein A.
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Reacts with: Human, Mouse, Rat, Chicken, Dog, Cow, Horse, Rabbit, .
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Immunogen: KLH conjugated synthetic peptide derived from human Epsin 3.
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Predicted Molecular Weight: Anti-Epsin 3抗體68kDa.
Storage:
Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
Not yet tested in other applications. Anti-Epsin 3抗體
Optimal working dilutions must be determined by the end user.
Not yet tested in other applications. Anti-Epsin 3抗體
Optimal working dilutions must be determined by the end user.
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