產品詳情
簡單介紹:
Anti-Collagen II抗體產品質量穩(wěn)定,實驗效果明顯,貨期快,價格優(yōu)惠,歡迎垂詢訂購!我公司長期供應**組化抗體、WB抗體、**組化試劑盒和抗體試驗所需全部相關試劑、熒光標記抗體、單克隆抗體、多克隆抗體、各種標記的二抗IgG/IgM/IgD/IgA等科研實驗抗體。Anti-Collagen II抗體用于**組化實驗,WB實驗,相應的標記抗體有HRP標記抗體,FITC標記,BIO等。
詳情介紹:
Rabbit Anti-Collagen II
Cat. Number:
Anti-Collagen II抗體KL-8859R
Quantity size:
0.2ml
Concentration:
1mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
Collagens are highly conserved throughout evolution and are characterized by an uninterrupted "Glycine-X-Y" triplet repeat that is a necessary part of the triple helical structure. For these reasons it is often extremely difficult to generate antibodies with specificities to collagens. The development of type specific antibodies is dependent on NON DENATURED three dimensional epitopes. This may result in diminished reactivity of some antibodies with denatured collagen or formalin fixed, paraffin embedded tissues. Anti-Collagen II抗體Type II collagen is a fibrillar collagen found in cartilage and the vitreous humor of the eye. Collagen type II is essential for the normal embryonic development of the skeleton, for linear growth and for the ability of cartilage to resist compressive forces. Mutations in this gene are associated with achondrogenesis, chondrodysplasia, early onset familial osteoarthritis, SED congenita, Langer Saldino achondrogenesis, Kniest dysplasia, Stickler syndrome type I, and spondyloepimetaphyseal dysplasia Strudwick type. In addition, defects in processing chondrocalcin, a calcium binding protein that is the C propeptide of this collagen molecule, are also associated with chondrodysplasia. There are two transcripts identified for this gene.
Also known as:
Collagen II alpha 1; Anti-Collagen II抗體COL2A1; COL2A1 protein; collagen, type II, alpha 1; collagen alpha-1(II); type II collagen; alpha-1 type II collagen; alpha1 type II collagen; Col2a1; AOM; Cartilage collagen; Chondrocalcin; COL11A3; Collagen alpha 1(II) chain precursor; Collagen II alpha 1 polypeptide; Collagen type II alpha 1 (primary osteoarthritis spondyloepiphyseal dysplasia congenital); MGC131516; SEDC; CO2A1_HUMAN.
Specificity:
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Rabbit Polyclonal IgG, affinity purified by Protein A.
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Reacts with: Human, Mouse, Rat, Chicken, Pig, Horse, Rabbit, Bovine, .
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Immunogen: KLH conjugated synthetic peptide derived from human Collagen alpha-1(II) chain.
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Predicted Molecular Weight: 117kDa.
Storage:
Shipped at 4℃, Anti-Collagen II抗體Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
IHC-P=1:100-500 IHC-F=1:100-500
Not yet tested in other applications.
Optimal working Anti-Collagen II抗體dilutions must be determined by the end user.
Not yet tested in other applications.
Optimal working Anti-Collagen II抗體dilutions must be determined by the end user.
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