產品詳情
簡單介紹：
Anti-phospho-CASC3(Tyr181)抗體產品質量穩定，實驗效果明顯，貨期快，價格優惠，歡迎垂詢訂購！我公司長期供應**組化抗體、WB抗體、**組化試劑盒和抗體試驗所需全部相關試劑、熒光標記抗體、單克隆抗體、多克隆抗體、各種標記的二抗IgG/IgM/IgD/IgA等科研實驗抗體。Anti-phospho-CASC3(Tyr181)抗體用于**組化實驗,WB實驗,相應的標記抗體有HRP標記抗體,FITC標記,BIO等。
詳情介紹：
Rabbit Anti-phospho-CASC3(Tyr181)
Cat. Number:
Anti-phospho-CASC3(Tyr181)抗體KL-5283R
Quantity size:
0.1ml
Concentration:
1mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
The multiprotein exon junction complex (EJC) is deposited on mRNAs upstream of exon–exon junctions as a consequence of pre-mRNA splicing. In mammalian cells, this complex serves as a key modulator of spliced mRNA metabolism. MLN51 is a nucleocytoplasmic shuttling protein that is overexpressed in breast cancer. The function of MLN51 in mammals remains elusive. Its fly homolog, named barentsz, as well Anti-phospho-CASC3(Tyr181)抗體as the proteins mago nashi and tsunagi have been shown to be required for proper oskar mRNA localization to the posterior pole of the oocyte. Magoh and Y14, the human homologs of mago nashi and tsunagi, are core components of the exon junction complex (EJC). The EJC is assembled on spliced mRNAs and plays important roles in post-splicing events including mRNA export, nonsense-mediated mRNA decay, and translation. Human MLN51 is an RNA-binding protein present in ribonucleo-protein complexes.
Also known as:
Barentsz protein; Btz; Cancer susceptibility candidate gene 3 protein; Metastatic lymph node protein 51; MLN 51 protein; MLN51;Anti-phospho-CASC3(Tyr181)抗體 Protein barentsz; Protein CASC3; Protein MLN 51; CASC3_HUMAN.
Specificity:
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Rabbit Polyclonal IgG, affinity purified by Protein A.
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Reacts with: Human, Mouse, Rat, Chicken, Pig, Cow, Horse, Rabbit, .
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Immunogen: KLH conjugated Synthesised phosphopeptide derived from human CASC3 around the phosphorylation site of Tyr181.
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Predicted Molecular Weight: 76kDa.
Storage:
Shipped at 4℃, Store at -20℃ Anti-phospho-CASC3(Tyr181)抗體(Avoid repeated freeze/thaw cycles).
Application:
WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
Not yet tested in other applications.
Optimal working dilutions Anti-phospho-CASC3(Tyr181)抗體must be determined by the end user.
Not yet tested in other applications.
Optimal working dilutions Anti-phospho-CASC3(Tyr181)抗體must be determined by the end user.
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