產(chǎn)品詳情
簡單介紹：
Anti-phospho-CREB-1(Ser129)抗體產(chǎn)品質(zhì)量穩(wěn)定，實驗效果明顯，貨期快，價格優(yōu)惠，歡迎垂詢訂購！我公司長期供應(yīng)**組化抗體、WB抗體、**組化試劑盒和抗體試驗所需全部相關(guān)試劑、熒光標(biāo)記抗體、單克隆抗體、多克隆抗體、各種標(biāo)記的二抗IgG/IgM/IgD/IgA等科研實驗抗體。Anti-phospho-CREB-1(Ser129)抗體用于**組化實驗,WB實驗,相應(yīng)的標(biāo)記抗體有HRP標(biāo)記抗體,FITC標(biāo)記,BIO等。
詳情介紹：
Rabbit Anti-phospho-CREB-1(Ser129)
Cat. Number:
Anti-phospho-CREB-1(Ser129)抗體KL-5256R
Quantity size:
0.1ml
Concentration:
1mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
The ATF/CREB family consists of transcription factors that function through binding to the cAMP responsive element (CRE) palindromic octanucleotide, TGACCTCA. The best characterized members of this gene family include CREB-1, CREB-2, ATF-1,ATF-2,ATF-3and ATF-4. these transcription factors share highly-related COOH terminal leucine zipper demerization and basic DNA bindings but are highly Anti-phospho-CREB-1(Ser129)抗體divergent in their amino terminal domains. Although each of the ATF/CREB proteins bind CREs in their homodimeric form, in cerain instances they also bind as heterodimers, both within the ATF/CREB family and with members of the AP-1 transcription factor family. It has recentlybeen shown that protein kinase A-mediated CREB phosphorylation results in its binding to a 265kDa nuclear protein designated CBP (CREB-binding protein), which may reprecent a CREB co-activator.
Also known as:
CREB(Phospho-Ser129);Anti-phospho-CREB-1(Ser129)抗體 p-CREB-1(Ser129); pCREB-1(Ser129); CREB (phospho S121) ; p-CREB (phospho S121); Active transcription factor CREB; cAMP response element binding protein; cAMP responsive element binding protein 1; CREB1; CREB 1; CREB1; MGC9284; Transactivator protein; CREB; CREB1_HUMAN.
Specificity:
●
Rabbit Polyclonal IgG, affinity purified by Protein A.
●
Reacts with: Human, Mouse, Rat, Pig, Horse, Sheep, .
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Immunogen: KLH conjugated Synthesised phosphopeptide derived from human CREB-1 around the phosphorylation site of Ser129 [IL(p-S)RR].
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Predicted Molecular Weight: 37kDa.
Storage:
Shipped at 4℃, Store at -20℃Anti-phospho-CREB-1(Ser129)抗體 (Avoid repeated freeze/thaw cycles).
Application:
WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
Not yet tested in other applications.
Optimal working dilutionsAnti-phospho-CREB-1(Ser129)抗體 must be determined by the end user.
Not yet tested in other applications.
Optimal working dilutionsAnti-phospho-CREB-1(Ser129)抗體 must be determined by the end user.
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