產(chǎn)品詳情
簡單介紹：
Anti-phospho-CDKN2A (Ser8)抗體產(chǎn)品質(zhì)量穩(wěn)定，實驗效果明顯，貨期快，價格優(yōu)惠，歡迎垂詢訂購！我公司長期供應**組化抗體、WB抗體、**組化試劑盒和抗體試驗所需全部相關試劑、熒光標記抗體、單克隆抗體、多克隆抗體、各種標記的二抗IgG/IgM/IgD/IgA等科研實驗抗體。Anti-phospho-CDKN2A (Ser8)抗體用于**組化實驗,WB實驗,相應的標記抗體有HRP標記抗體,FITC標記,BIO等。
詳情介紹：
Rabbit Anti-phospho-CDKN2A (Ser8)
Cat. Number:
Anti-phospho-CDKN2A (Ser8)抗體KL-5255R
Quantity size:
0.1ml
Concentration:
1mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
This gene generates several transcript variants which differ in their first exons. At least three alternatively spliced variants encoding distinct proteins have been reported, two of which encode structurally related isoforms known to function as inhibitors of CDK4 kinase. The remaining transcript includes an alternate first exon located 20 Kb upstream of the remainder of the gene; this transcript contains an alternate open reading frame (ARF) that specifies a protein which is structurally unrelated to the products of the Anti-phospho-CDKN2A (Ser8)抗體other variants. This ARF product functions as a stabilizer of the tumor suppressor protein p53 as it can interact with, and sequester, the E3 ubiquitin-protein ligase MDM2, a protein responsible for the degradation of p53. In spite of the structural and functional differences, the CDK inhibitor isoforms and the ARF product encoded by this gene, through the regulatory roles of CDK4 and p53 in cell cycle G1 progression, share a common functionality in cell cycle G1 control. This gene is frequently mutated or deleted in a wide variety of tumors, and is known to be an important tumor suppressor gene. [provided by RefSeq, Sep 2012].
Also known as:
p-CDKN2A/p16-INK4a(Ser8); p-p16-INK4a(Ser8); cyclin-dependent kinase inhibitor 2A;CDK4I; p16-INK4; p16-INK4a; Anti-phospho-CDKN2A (Ser8)抗體cyclin-dependent kinase 4 inhibitor A; cyclin-dependent kinase inhibitor 2A, isoform 1; Cyclin dependent kinase inhibitor 2A (p16, inhibits CDK4); cell cycle inhibitor; cyclin-dependent kinase inhibitor 2a p16Ink4a; cell cycle regulator; cyclin-dependent kinase inhibitor 2a p19Arf; cyclin-dependent kinase inhibitor 2A, isoform 2; Cdkn2a; Arf; INK4A; MTS1; p16; p16Cdkn2a; p19ARF; CD2A1_HUMAN.
Specificity:
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Rabbit Polyclonal IgG, affinity purified by Protein A.
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Reacts with: Human, .
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Immunogen: KLH conjugated Synthesised phosphopeptide derived from human CDKN2A around the phosphorylation site of Ser8 [GS(p-S)ME].
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Predicted Molecular Weight: 17kDa.
Storage:
Shipped at 4℃, Store Anti-phospho-CDKN2A (Ser8)抗體at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
Not yet tested in other applications.
Optimal working dilutionsAnti-phospho-CDKN2A (Ser8)抗體 must be determined by the end user.
Not yet tested in other applications.
Optimal working dilutionsAnti-phospho-CDKN2A (Ser8)抗體 must be determined by the end user.
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kl033Mu01 熱休克蛋白β8(HSPβ8)多克隆抗體 Polyclonal Antibody to Heat Shock Protein Beta 8 (HSPb8)
kl033Ra01 熱休克蛋白β8(HSPβ8)多克隆抗體 Polyclonal Antibody to Heat Shock Protein Beta 8 (HSPb8)
kl034Hu01 生長分化因子15(GDF15)多克隆抗體 Polyclonal Antibody to Growth Differentiation Factor 15 (GDF15)
kl034Mu01 生長分化因子15(GDF15)多克隆抗體 Polyclonal Antibody to Growth Differentiation Factor 15 (GDF15)
kl034Ra01 生長分化因子15(GDF15)多克隆抗體 Polyclonal Antibody to Growth Differentiation Factor 15 (GDF15)
kl035Hu01 S100鈣結合蛋白A7(S100A7)多克隆抗體 Polyclonal Antibody to S100 Calcium Binding Protein A7 (S100A7)
kl035Mu01 S100鈣結合蛋白A7(S100A7)多克隆抗體 Polyclonal Antibody to S100 Calcium Binding Protein A7 (S100A7)
kl040Hu01 葡萄糖轉運蛋白2(GLUT2)多克隆抗體 Polyclonal Antibody to Glucose Transporter 2 (GLUT2)
kl041Hu01 過氧化物酶體增殖物激活受體δ(Pklδ)多克隆抗體 Polyclonal Antibody to Peroxisome Proliferator Activated Receptor Delta (Pkld)
kl042Hu01 法尼酯X受體(FXR)多克隆抗體 Polyclonal Antibody to Farnesoid X Receptor (FXR)
kl042Mu01 法尼酯X受體(FXR)多克隆抗體 Polyclonal Antibody to Farnesoid X Receptor (FXR)
kl044Hu01 肝X受體α(LXRα)多克隆抗體 Polyclonal Antibody to Liver X Receptor Alpha (LXRa)
kl045Hu01 存活素(Surv)多克隆抗體 Polyclonal Antibody to Survivin (Surv)
kl045Mu01 存活素(Surv)多克隆抗體 Polyclonal Antibody to Survivin (Surv)
kl047Hu01 Ki-67蛋白(Ki67P)多克隆抗體 Polyclonal Antibody to Ki-67 Protein (Ki67P)
kl047Mu01 Ki-67蛋白(Ki67P)多克隆抗體 Polyclonal Antibody to Ki-67 Protein (Ki67P)
kl047Ra01 Ki-67蛋白(Ki67P)多克隆抗體 Polyclonal Antibody to Ki-67 Protein (Ki67P)
