產品詳情
簡單介紹：
Anti-Phospho-BRCA1 (Ser1423)抗體產品質量穩定，實驗效果明顯，貨期快，價格優惠，歡迎垂詢訂購！我公司長期供應**組化抗體、WB抗體、**組化試劑盒和抗體試驗所需全部相關試劑、熒光標記抗體、單克隆抗體、多克隆抗體、各種標記的二抗IgG/IgM/IgD/IgA等科研實驗抗體。Anti-Phospho-BRCA1 (Ser1423)抗體用于**組化實驗,WB實驗,相應的標記抗體有HRP標記抗體,FITC標記,BIO等。
詳情介紹：
Rabbit Anti-Phospho-BRCA1 (Ser1423)
Cat. Number:
Anti-Phospho-BRCA1 (Ser1423)抗體KL-5222R
Quantity size:
0.1ml
Concentration:
1mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
This gene encodes a nuclear phosphoprotein that plays a role in maintaining genomic stability, and it also acts as a tumor suppressor. The encoded protein combines with other tumor suppressors, DNA damage sensors, andAnti-Phospho-BRCA1 (Ser1423)抗體 signal transducers to form a large multi-subunit protein complex known as the BRCA1-associated genome surveillance complex (BASC). This gene product associates with RNA polymerase II, and through the C-terminal domain, also interacts with histone deacetylase complexes. This protein thus plays a role in transcription, DNA repair of double-stranded breaks, and recombination. Mutations in this gene are responsible for approximately 40% of inherited breast cancers and more than 80% of inherited breast and ovarian cancers. Alternative splicing plays a role in modulating the subcellular localization and physiological function of this gene. Many alternatively spliced transcript variants, some of which are disease-associated mutations, have been described for this gene, but the full-length natures of only some of these variants has been described. A related pseudogene, which is also located on chromosome 17, has been identified. Anti-Phospho-BRCA1 (Ser1423)抗體[provided by RefSeq, May 2009].
Also known as:
BRCA 1; BRCA1; BRCA1/BRCA2 containing complex subunit 1; BRCA1/BRCA2-containing complex, subunit 1; Anti-Phospho-BRCA1 (Ser1423)抗體BRCA1_HUMAN; BRCAI; BRAC 1; BRCA 1; BRCC 1; BRCC1; Breast Cancer 1; Breast Cancer 1 Early Onset; Breast cancer type 1 susceptibility protein; Breast and ovarian cancer susceptibility protein 1; Breast Ovarian Cancer Susceptibility; IRIS; Papillary Serous Carcinoma Of The Peritoneum; PSCP; RING finger protein 53; BROVCA1; IRIS; PNCA4; PPP1R53; Protein phosphatase 1 regulatory subunit 53; RNF53; BAP1.
Specificity:
●
Rabbit Polyclonal IgG, affinity purified by Protein A.
●
Reacts with: Human, .
●
Immunogen: KLH conjugated Synthesised phosphopeptide derived from human BRCA1 around the phosphorylation site of Ser1423.
●
Predicted Molecular Weight: 202kDa.
Storage:
Shipped at 4℃, Anti-Phospho-BRCA1 (Ser1423)抗體Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
Not yet tested in other applications.
Optimal working Anti-Phospho-BRCA1 (Ser1423)抗體dilutions must be determined by the end user.
Not yet tested in other applications.
Optimal working Anti-Phospho-BRCA1 (Ser1423)抗體dilutions must be determined by the end user.
kl464Hu01 鹽皮質**受體(MR)多克隆抗體 Polyclonal Antibody to Mineralocorticoid Receptor (MR)
kl464Ra01 鹽皮質**受體(MR)多克隆抗體 Polyclonal Antibody to Mineralocorticoid Receptor (MR)
kl468Hu01 衰變加速因子(DAF)多克隆抗體 Polyclonal Antibody to Decay Accelerating Factor (DAF)
kl470Hu01 熱休克轉錄因子2(HSF2)多克隆抗體 Polyclonal Antibody to Heat Shock Transcription Factor 2 (HSF2)
kl471Bo01 骨鈣素(OC)多克隆抗體 Polyclonal Antibody to Osteocalcin (OC)
kl471Ca01 骨鈣素(OC)多克隆抗體 Polyclonal Antibody to Osteocalcin (OC)
kl471Hu01 骨鈣素(OC)多克隆抗體 Polyclonal Antibody to Osteocalcin (OC)
kl471Mu01 骨鈣素(OC)多克隆抗體 Polyclonal Antibody to Osteocalcin (OC)
kl471Po01 骨鈣素(OC)多克隆抗體 Polyclonal Antibody to Osteocalcin (OC)
kl471Ra01 骨鈣素(OC)多克隆抗體 Polyclonal Antibody to Osteocalcin (OC)
kl471Rb51 骨鈣素(OC)多克隆抗體 Polyclonal Antibody to Osteocalcin (OC)
kl472Ca01 降鈣素(CT)多克隆抗體 Polyclonal Antibody to Calcitonin (CT)
kl472Hu01 降鈣素(CT)多克隆抗體 Polyclonal Antibody to Calcitonin (CT)
kl472Mu01 降鈣素(CT)多克隆抗體 Polyclonal Antibody to Calcitonin (CT)
kl472Ra01 降鈣素(CT)多克隆抗體 Polyclonal Antibody to Calcitonin (CT)
kl473Hu01 C組著色性干皮病偶聯因子(XPC)多克隆抗體 Polyclonal Antibody to Xeroderma Pigmentosum, Complementation Group C (XPC)
kl473Mu01 C組著色性干皮病偶聯因子(XPC)多克隆抗體 Polyclonal Antibody to Xeroderma Pigmentosum, Complementation Group C (XPC)
kl474Hu01 甲狀旁腺素受體2(PTHR2)多克隆抗體 Polyclonal Antibody to klathyroid Hormone Receptor 2 (PTHR2)
kl474Ra01 甲狀旁腺素受體2(PTHR2)多克隆抗體 Polyclonal Antibody to klathyroid Hormone Receptor 2 (PTHR2)
kl475Hu01 維生素D受體(VDR)多克隆抗體 Polyclonal Antibody to Vitamin D Receptor (VDR)
kl475Mu01 維生素D受體(VDR)多克隆抗體 Polyclonal Antibody to Vitamin D Receptor (VDR)
