產品詳情
簡單介紹：
Anti-phospho-ARP3 (Ser418)抗體產品質量穩定，實驗效果明顯，貨期快，價格優惠，歡迎垂詢訂購！我公司長期供應**組化抗體、WB抗體、**組化試劑盒和抗體試驗所需全部相關試劑、熒光標記抗體、單克隆抗體、多克隆抗體、各種標記的二抗IgG/IgM/IgD/IgA等科研實驗抗體。Anti-phospho-ARP3 (Ser418)抗體用于**組化實驗,WB實驗,相應的標記抗體有HRP標記抗體,FITC標記,BIO等。
詳情介紹：
Rabbit Anti-phospho-ARP3 (Ser418)
Cat. Number:
Anti-phospho-ARP3 (Ser418)抗體KL-8999R
Quantity size:
0.1ml
Concentration:
1mg/ml Buffer = 0.01M Anti-phospho-ARP3 (Ser418)抗體TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
Actin polymerization is required for a variety of cell functions, including chemotaxis, cell migration, cell adhesion, and platelet activation. Cells trigger actin polymerization through either the de novo nucleation of filaments from monomeric actin, the severing of existing filaments to create uncapped barbed ends, or the Anti-phospho-ARP3 (Ser418)抗體uncapping existing barbed ends. The nucleation of actin is a rate-limiting and unfavorable reaction in actin polymerization and therefore requires the involvement of the Arp2/3 complex, which helps create new filaments and promotes the end-to-side cross-linking of actin filaments into the branching meshwork. The Arp2/3 complex consists of the actin-related proteins Arp2 and Arp3, and various other accessory proteins. The Arp2/3 complex promotes actin nucleation by binding the pointed end of actin filaments, or by associating with the side of an existing filament, and nucleates growth in the barbed direction. In addition, the Arp2/3 complex also mediates actin cytoskeletal outgrowths that are regulated by the Rho family of small GTPases. In response to GTP-binding Cdc42, the Arp2/3 complex binds the Cdc42 substrates, Anti-phospho-ARP3 (Ser418)抗體namely the WASP proteins, and initiates the formation of lamellipodia and filopodia.
Also known as:
ARP3 (phospho-Ser418); ARP3 (phospho S418); Actin-like protein 3; Actin-related protein 3; ACTR3; ARP3 Anti-phospho-ARP3 (Ser418)抗體actin-related protein 3 homolog; ARP3_HUMAN.
Specificity:
●
Rabbit Polyclonal IgG, affinity purified by Protein A.
●
Reacts with: Human, Mouse, Rat, .
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Immunogen: KLH conjugated synthetic peptide derived from human phospho-ARP3 (Ser418).
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Predicted Molecular Weight: 47kDa.
Storage:
Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
Not yet tested in other applications.
Optimal working Anti-phospho-ARP3 (Ser418)抗體dilutions must be determined by the end user.
Not yet tested in other applications.
Optimal working Anti-phospho-ARP3 (Ser418)抗體dilutions must be determined by the end user.
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