產(chǎn)品詳情
簡單介紹：
Anti-phospho-AKT1 (Ser473 + Tyr474)抗體產(chǎn)品質(zhì)量穩(wěn)定，實驗效果明顯，貨期快，價格優(yōu)惠，歡迎垂詢訂購！我公司長期供應(yīng)**組化抗體、WB抗體、**組化試劑盒和抗體試驗所需全部相關(guān)試劑、熒光標(biāo)記抗體、單克隆抗體、多克隆抗體、各種標(biāo)記的二抗IgG/IgM/IgD/IgA等科研實驗抗體。Anti-phospho-AKT1 (Ser473 + Tyr474)抗體用于**組化實驗,WB實驗,相應(yīng)的標(biāo)記抗體有HRP標(biāo)記抗體,FITC標(biāo)記,BIO等。
詳情介紹：
Rabbit Anti-phospho-AKT1 (Ser473 + Tyr474)
Cat. Number:
Anti-phospho-AKT1 (Ser473 + Tyr474)抗體KL-10134R
Quantity size:
0.1ml
Concentration:
1mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
AKT, also known as protein kinase B (PKB), is a 57 kDa serine/threonine protein kinase. There are three mammalian isoforms of Akt: AKT1 (PKB alpha), AKT2 (PKB beta) and AKT3 (PKB gamma) with AKT2 and AKT3 Anti-phospho-AKT1 (Ser473 + Tyr474)抗體being approximately 82% identical with the AKT1 isoform. Each isoform has a pleckstrin homology (PH)domain, a kinase domain and a carboxy terminal regulatory domain. AKT was originally cloned from the retrovirus AKT8, and is a key regulator of many signal transduction pathways. Its tight control over cell proliferation and cell viability are manifold; overexpression or inappropriate activation of AKT has been seen in many types of cancer. AKT mediates many of the downstream events of phosphatidylinositol 3 kinase (a lipid kinase activated by growth factors, cytokines and insulin). PI3 kinase recruits AKT to the membrane, where it is activated by PDK1 phosphorylation. Once phosphorylated, AKT dissociates from the membrane and phosphorylates targets in the cytoplasm and the cell nucleus.
Also known as:
AKT1(phospho Anti-phospho-AKT1 (Ser473 + Tyr474)抗體Ser473/Tyr474); phospho-AKT1 (Ser473/Tyr474); AKT1 (phospho S473); AKT 1; AKT; AKT1; AKT-1; AKT1_HUMAN; C AKT; cAKT; MGC9965; MGC99656; Oncogene AKT1; PKB; PKB alpha; PKB-ALPHA; PRKBA; Protein Kinase B Alpha; Protein kinase B; Proto-oncogene c-Akt; RAC Alpha; RAC alpha serine/threonine protein kinase; RAC; RAC PK Alpha; Rac protein kinase alpha; RAC Serine/Threonine Protein Kinase; RAC-alpha serine/threonine-protein kinase; RAC-PK-alpha; v akt murine thymoma viral oncogene homolog 1; vAKT Murine Thymoma Viral Oncogene Homolog 1.
Specificity:
●
Rabbit Polyclonal IgG, affinity purified by Protein A.
●
Reacts with: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Rabbit, Sheep, .
●
Immunogen: KLH conjugated synthesised phosphopeptide derived from human AKT1 around the phosphorylation site of Ser473/Tyr474.
●
Predicted Molecular Anti-phospho-AKT1 (Ser473 + Tyr474)抗體Weight: 56kDa.
Storage:
Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
Not yet tested in other applications.
Optimal working Anti-phospho-AKT1 (Ser473 + Tyr474)抗體dilutions must be determined by the end user.
Not yet tested in other applications.
Optimal working Anti-phospho-AKT1 (Ser473 + Tyr474)抗體dilutions must be determined by the end user.
kl630Ra01 糖原合酶激酶3α(GSK3α)多克隆抗體 Polyclonal Antibody to Glycogen Synthase Kinase 3 Alpha (GSK3a)
kl631Hu01 中期因子(MK)多克隆抗體 Polyclonal Antibody to Midkine (MK)
kl631Mu01 中期因子(MK)多克隆抗體 Polyclonal Antibody to Midkine (MK)
kl631Ra01 中期因子(MK)多克隆抗體 Polyclonal Antibody to Midkine (MK)
kl635Hu01 補體因子H(CFH)多克隆抗體 Polyclonal Antibody to Complement Factor H (CFH)
kl635Mu01 補體因子H(CFH)多克隆抗體 Polyclonal Antibody to Complement Factor H (CFH)
kl635Ra01 補體因子H(CFH)多克隆抗體 Polyclonal Antibody to Complement Factor H (CFH)
kl636Hu01 成纖維細(xì)胞生長因子7(FGF7)多克隆抗體 Polyclonal Antibody to Fibroblast Growth Factor 7 (FGF7)
kl636Mu01 成纖維細(xì)胞生長因子7(FGF7)多克隆抗體 Polyclonal Antibody to Fibroblast Growth Factor 7 (FGF7)
kl636Po01 成纖維細(xì)胞生長因子7(FGF7)多克隆抗體 Polyclonal Antibody to Fibroblast Growth Factor 7 (FGF7)
kl636Ra01 成纖維細(xì)胞生長因子7(FGF7)多克隆抗體 Polyclonal Antibody to Fibroblast Growth Factor 7 (FGF7)
kl637Hu01 氨基己糖苷酶Bβ(HEXβ)多克隆抗體 Polyclonal Antibody to Hexosaminidase B Beta (HEXb)
kl637Mu01 氨基己糖苷酶Bβ(HEXβ)多克隆抗體 Polyclonal Antibody to Hexosaminidase B Beta (HEXb)
kl637Ra01 氨基己糖苷酶Bβ(HEXβ)多克隆抗體 Polyclonal Antibody to Hexosaminidase B Beta (HEXb)
kl638Bo01 內(nèi)脂素(VF)多克隆抗體 Polyclonal Antibody to Visfatin (VF)
kl638Hu01 內(nèi)脂素(VF)多克隆抗體 Polyclonal Antibody to Visfatin (VF)
kl638Mu01 內(nèi)脂素(VF)多克隆抗體 Polyclonal Antibody to Visfatin (VF)
kl638Ra01 內(nèi)脂素(VF)多克隆抗體 Polyclonal Antibody to Visfatin (VF)
kl642Ra01 果糖二磷酸醛縮酶A(ALDOA)多克隆抗體 Polyclonal Antibody to Aldolase A, Fructose Bisphosphate (ALDOA)
kl644Hu01 CCAAT增強(qiáng)子結(jié)合蛋白α(CEBPα)多克隆抗體 Polyclonal Antibody to CCAAT/Enhancer Binding Protein Alpha (CEBPa)
kl645Hu01 晚期糖基化終末產(chǎn)物受體(AGER)多克隆抗體 Polyclonal Antibody to Advanced Glycosylation End Product Specific Receptor (AGER)
