產品詳情
簡單介紹：
Anti-ATF2抗體產品質量穩定，實驗效果明顯，貨期快，價格優惠，歡迎垂詢訂購！我公司長期供應**組化抗體、WB抗體、**組化試劑盒和抗體試驗所需全部相關試劑、熒光標記抗體、單克隆抗體、多克隆抗體、各種標記的二抗IgG/IgM/IgD/IgA等科研實驗抗體。Anti-ATF2抗體用于**組化實驗,WB實驗,相應的標記抗體有HRP標記抗體,FITC標記,BIO等。
詳情介紹：
Rabbit Anti-ATF2
Cat. Number:
KL-0518R
Quantity size:
0.2ml
Concentration:
Anti-ATF2抗體1mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
Anti-ATF2抗體ATF2 is a member of the ATF/CREB family of basic region leucine zipper DNA binding proteins that regulates transcription by binding to a consensus cAMP response element (CRE) in the promoter of various viral and cellular genes. Many of these genes are important in cell growth and differentiation, and in stress and immune responses. ATF2 is a nuclear protein that binds DNA as a dimer and can form dimers with members of the ATF/CREB and Jun/Fos families. It is a stronger activator as a heterodimer with cJun than as a homodimer. Several isoforms of ATF2 arise by differential splicing. The stable native full length ATF2 is transcriptionally inactive as a result of an inhibitory direct intramolecular interaction of its carboxy terminal DNA binding domain with the amino terminal transactivation domain. Following dimerization ATF2 becomes a short lived protein that undergoes ubiquitination and proteolysis, seemingly in a protein phosphatase-dependent mechanism. Stimulation of the transcriptional activity of ATF2 occurs following cellular stress induced by several genotoxic agents, inflammatory cytokines, and UV irradiation. This activation requires phosphorylation of two threonine residues in ATF2 by both JNK/SAP kinase and p38 MAP kinase. ATF2 is abundantly expressed in brain.
Also known as:
Anti-ATF2抗體CREB 2; HB 16; Activating Transcription Factor 2; ATF 2; Atf-2; ATF2 protein; cAMP Response Element Binding Protein 2; cAMP response element binding protein CRE BP1; cAMP-dependent transcription factor ATF-2; cAMP-responsive element-binding protein 2; CRE BP1; CRE-BP; CREB 2; CREB2; CREBP1; Cyclic AMP dependent transcription factor ATF 2; Cyclic AMP-responsive element-binding protein 2; HB 16; HB16; ATF2_HUMAN.
Specificity:
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Rabbit Polyclonal IgG, affinity purified by Protein A.
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Reacts with: Human, Mouse, Rat, .
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Immunogen: KLH conjugated synthetic peptide derived from human ATF2 C-terminus.
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Predicted Molecular Weight: 55kDa.
Storage:
Anti-ATF2抗體Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
Anti-ATF2抗體WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.kl817Ra01 無翅型MMTV整合位點家族成員4(WNT4)多克隆抗體 Polyclonal Antibody to Wingless Type MMTV Integration Site Family, Member 4 (WNT4)
kl818Hu01 無翅型MMTV整合位點家族成員3(WNT3)多克隆抗體 Polyclonal Antibody to Wingless Type MMTV Integration Site Family, Member 3 (WNT3)
kl820Hu01 無翅型MMTV整合位點家族成員2(WNT2)多克隆抗體 Polyclonal Antibody to Wingless Type MMTV Integration Site Family, Member 2 (WNT2)
kl821Hu01 無翅型MMTV整合位點家族成員1(WNT1)多克隆抗體 Polyclonal Antibody to Wingless Type MMTV Integration Site Family, Member 1 (WNT1)
kl826Hu01 WNT抑制因子1(WIF1)多克隆抗體 Polyclonal Antibody to WNT Inhibitory Factor 1 (WIF1)
kl838Hu01 卵巢腫瘤蛋白1(OTUB1)多克隆抗體 Polyclonal Antibody to Otubain 1 (OTUB1)
kl872Hu01 USP6氨基端樣蛋白(USP6NL)多克隆抗體 Polyclonal Antibody to USP6 N-Terminal Like Protein (USP6NL)
kl882Hu01 UL16結合蛋白2(ULBP2)多克隆抗體 Polyclonal Antibody to UL16 Binding Brotein 2 (ULBP2)
kl907Ra01 N-myc下游調節基因2(NDRG2)多克隆抗體 Polyclonal Antibody to N-myc Downstream Regulated Gene 2 (NDRG2)
kl915Hu01 Nei內切核酸酶Ⅷ樣蛋白1(NEIL1)多克隆抗體 Polyclonal Antibody to Nei Endonuclease VIII Like Protein 1 (NEIL1)
kl917Hu01 信號素3A(SEMA3A)多克隆抗體 Polyclonal Antibody to Semaphorin 3A (SEMA3A)
kl917Ra01 信號素3A(SEMA3A)多克隆抗體 Polyclonal Antibody to Semaphorin 3A (SEMA3A)
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.kl817Ra01 無翅型MMTV整合位點家族成員4(WNT4)多克隆抗體 Polyclonal Antibody to Wingless Type MMTV Integration Site Family, Member 4 (WNT4)
kl818Hu01 無翅型MMTV整合位點家族成員3(WNT3)多克隆抗體 Polyclonal Antibody to Wingless Type MMTV Integration Site Family, Member 3 (WNT3)
kl820Hu01 無翅型MMTV整合位點家族成員2(WNT2)多克隆抗體 Polyclonal Antibody to Wingless Type MMTV Integration Site Family, Member 2 (WNT2)
kl821Hu01 無翅型MMTV整合位點家族成員1(WNT1)多克隆抗體 Polyclonal Antibody to Wingless Type MMTV Integration Site Family, Member 1 (WNT1)
kl826Hu01 WNT抑制因子1(WIF1)多克隆抗體 Polyclonal Antibody to WNT Inhibitory Factor 1 (WIF1)
kl838Hu01 卵巢腫瘤蛋白1(OTUB1)多克隆抗體 Polyclonal Antibody to Otubain 1 (OTUB1)
kl872Hu01 USP6氨基端樣蛋白(USP6NL)多克隆抗體 Polyclonal Antibody to USP6 N-Terminal Like Protein (USP6NL)
kl882Hu01 UL16結合蛋白2(ULBP2)多克隆抗體 Polyclonal Antibody to UL16 Binding Brotein 2 (ULBP2)
kl907Ra01 N-myc下游調節基因2(NDRG2)多克隆抗體 Polyclonal Antibody to N-myc Downstream Regulated Gene 2 (NDRG2)
kl915Hu01 Nei內切核酸酶Ⅷ樣蛋白1(NEIL1)多克隆抗體 Polyclonal Antibody to Nei Endonuclease VIII Like Protein 1 (NEIL1)
kl917Hu01 信號素3A(SEMA3A)多克隆抗體 Polyclonal Antibody to Semaphorin 3A (SEMA3A)
kl917Ra01 信號素3A(SEMA3A)多克隆抗體 Polyclonal Antibody to Semaphorin 3A (SEMA3A)
